Why are women's brains vulnerable at midlife — and what can we actually do about it?
Professor of Medicine (Neurology), University of Toronto
Jay & Sari Sonshine Chair in Stroke Prevention & Cerebrovascular Brain Health
Founder, HER PRISM™
"Midlife is the window where vulnerability becomes wisdom."
— Aleksandra Pikula, MDSix surfaces, one through-line: women's brain health.
Midlife is the decisive, modifiable window for women's brain health — where vascular risk, the menopause transition, and lifestyle converge to shape lifelong stroke and dementia risk.
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Up to 80% of strokes and 45% of dementia are preventable.
Midlife is the window to change the trajectory of women's brain health.
Working across institutions on women's brain health, stroke and dementia prevention.
Keynotes and workshops on women's brain health, the midlife transition, and physician burnout.
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Two engagements confirmed for Fall 2026.
Long-form essays and notes on women's brain health and the lived experience of being a woman in medicine — on Substack, with a companion newsletter on LinkedIn.
Speaking, media, and research collaboration. For coaching, visit herprism.co.